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Full Version: Dads, not just moms, can pass along mitochondrial DNA
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In rare cases, kids can inherit the energy-producing organelles from fathers, a study finds

Some dads have broken a textbook genetic rule. Fathers in three unrelated families passed mitochondria — tiny energy factories found in cells — on to their children, researchers report.

Scientists have long thought that children inherited mitochondria exclusively from their mothers, since mitochondria from the father’s sperm are usually destroyed after fertilizing the egg (SN: 1/1/00, p. 5). The new research, published online November 26 in the Proceedings of the National Academy of Sciences, suggests that in rare cases dads can contribute mitochondria too. For now, the consequences of inheriting mitochondria from both parents aren’t known.

Mitochondrial disease researcher Paldeep Atwal spotted the paternal signature after examining DNA from a woman who came to the Mayo Clinic in Jacksonville, Fla. DNA in a cell’s nucleus is inherited equally from both parents and contains all the genetic instructions for building a body. Mitochondria have their own DNA, too, that contains some of the genes needed for building and running the organelles. The woman’s cells weirdly contained two types of mitochondrial DNA, some from mom and some “from elsewhere,” says Atwal, who now runs a private clinic in Jacksonville.

https://www.sciencenews.org/article/dads...dna?tgt=nr


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